Key Publications
Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine.
Kathuria A, Lopez-Lengowski K, Watmuff B, McPhie D, Cohen BM, Karmacharya R.
Transl Psychiatry. 2019 11 28; 9(1):321. PMID: 31780643.
Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder.
Kathuria A, Lopez-Lengowski K, Vater M, McPhie D, Cohen BM, Karmacharya R.
Genome Med. 2020 04 19; 12(1):34. PMID: 32306996.
Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia.
Kathuria A, Lopez-Lengowski K, Jagtap SS, McPhie D, Perlis RH, Cohen BM, Karmacharya R.
JAMA Psychiatry. 2020 07 01; 77(7):745-754. PMID: 32186681.
Comparative Transcriptomic Analysis of Cerebral Organoids and Cortical Neuron Cultures Derived from Human Induced Pluripotent Stem Cells
Kathuria A, Lopez-Lengowski K, Watmuff B, Karmacharya R.
Stem Cells Dev. 2020 11 01; 29(21):1370-1381. PMID: 32862797.
Distinct effects of interleukin-6 and interferon-γ on differentiating human cortical neurons, Brain, Behavior, and Immunity
Annie Kathuria, Kara Lopez-Lengowski, Joshua L. Roffman, Rakesh Karmacharya,
2022, ISSN 0889-1591.
Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and cortical neurons in schizophrenia and bipolar disorder
Kathuria, A., Lopez-Lengowski, K., McPhie, D. et al.
Discov Ment Health 3, 8 (2023).